Metabolomics

Multi-platform analytical instrumentation such as nuclear magnetic resonance spectroscopy (NMR), gas chromatography mass spectrometry (GC-MS), and liquid chromatography-MS (LC-MS), are available at DHMRI, and used, either alone or in combination, for customized metabolomics analyses.

Uniquely positioned to provide high throughput metabolomic analysis from a single compound to whole metabolomes, the metabolomics core lab has the technology to cover the largest dynamic range to provide a complete understanding of their relationship with the biological system. Coupled with genomics and proteomics, DHMRI provides a much needed systems biology approach.

• Full spectrum Metabolomics approach utilizing LC, GC, and ICP based profiling for high throughput chemical marker discovery
• Automated sample preparation
• A compound library containing known and unknown metabolites
• Structure elucidation utilizing NMR, exact mass, and MSn

Data Analysis:

• Utilization of multivariate statistical analysis (PCA, HCA, etc.)
• Development of self organized maps/analysis
• Predictive analysis based on PLS, ANN tools

Metabolomics Home

GC-MS Based
LC-MS Based
ICP-MS Based
NMR Based

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